GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs4820294 | 1 | rs62236667 | chr22:38061520 | SH3BP1 | chr22:38030661-38062939:+ | 0.11 | 3.56 | 0.000403 | Fat distribution (HIV) |
| THCA | cis | rs4820294 | 1 | rs62236668 | chr22:38063870 | LGALS2 | chr22:37966254-37976024:- | 0.13 | 3.52 | 0.000477 | Fat distribution (HIV) |
| THCA | cis | rs4820294 | 1 | rs62236668 | chr22:38063870 | PDXP | chr22:38054737-38062939:+ | -0.18 | -3.38 | 0.000775 | Fat distribution (HIV) |
| THCA | cis | rs4820294 | 1 | rs62236668 | chr22:38063870 | SH3BP1 | chr22:38030661-38062939:+ | 0.11 | 3.56 | 0.000403 | Fat distribution (HIV) |
| THCA | cis | rs7647973 | 1 | rs62259933 | chr3:49469703 | GMPPB | chr3:49758932-49761384:- | 0.16 | 3.72 | 0.000221 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62259933 | chr3:49469703 | P4HTM | chr3:49027341-49044579:+ | -0.17 | -4.27 | 2.36E-5 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62259933 | chr3:49469703 | WDR6 | chr3:49044637-49053386:+ | 0.18 | 3.69 | 0.000251 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62259944 | chr3:49430883 | GMPPB | chr3:49758932-49761384:- | 0.18 | 3.88 | 0.000119 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62259944 | chr3:49430883 | P4HTM | chr3:49027341-49044579:+ | -0.19 | -4.6 | 5.36E-6 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62259947 | chr3:49439924 | GMPPB | chr3:49758932-49761384:- | 0.17 | 3.73 | 0.000218 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62259947 | chr3:49439924 | P4HTM | chr3:49027341-49044579:+ | -0.19 | -4.65 | 4.33E-6 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62261249 | chr3:49594060 | GMPPB | chr3:49758932-49761384:- | 0.16 | 3.62 | 0.000325 | Menarche (age at onset) |
| THCA | cis | rs7647973 | 1 | rs62261249 | chr3:49594060 | P4HTM | chr3:49027341-49044579:+ | -0.18 | -4.5 | 8.6E-6 | Menarche (age at onset) |
| THCA | cis | rs13067306 | 1 | rs62265556 | chr3:94243253 | STX19 | chr3:93733215-93747454:- | 0.28 | 3.43 | 0.000664 | Blood pressure measurement (high sodium intervention) |
| THCA | cis | rs3772130 | 1 | rs62268732 | chr3:121370455 | HCLS1 | chr3:121350247-121379791:- | -0.07 | -3.42 | 0.000668 | Cognitive performance |